Biography
She has worked at UCSF to develop interdisciplinary teams of clinicians and researchers to bring the best care to patients and find the best platform to integrate translational research and improve the delivery of breast cancer care. In 2005, she received the NCI SPORE Investigator of the Year Award, an internationally recognized honor and designation.
She is the Principal Investigator of the I-SPY TRIAL program, a multi-site neoadjuvant clinical trial that has evolved into a model for translational research and innovation in clinical trial design.
Dr. Esserman launched a University of California-wide breast cancer initiative called the Athena Breast Health Network, a project designed to follow 400,000 women from screening through treatment and outcomes, incorporating the latest in molecular testing and web-based tools into the course of care.
Dr. Esserman is nationally and internationally known as a leader in the field of breast cancer and has published over 200 articles in peer-reviewed journals covering all aspects of breast health including information systems, immunology, decision making, health policy and the use of imaging. She speaks extensively at public and private forums within the U.S. and internationally. Overall, Dr. Esserman's research and writing tends to focus on the goal of giving patients better access to accurate information so that they can become partners in their health care.
She was a member of President Obama’s Council of Advisors on Science and Technology (PCAST) Working Group on Advancing Innovation in Drug Development and Evaluation, which studied how the federal government can best support science-based innovation in the process of drug development and regulatory evaluation. In addition, she was a contributing member of a “taskforce” for President Obama’s Council of Advisors on Science and Technology.
Dr. Esserman received her Bachelor's degree in History of Science from Harvard University and completed her M.D. at Stanford University. She completed her surgery residency and oncology fellowship at Stanford University Medical Center. After her training, she joined the faculty at Stanford and received a Hartford fellowship to attend Stanford Business School where she received her M.B.A. in 1993. She then joined the faculty at the University of California, San Francisco.
Education
1974-77, Harvard University, A.B.
1978-83, Stanford University, M.D.
1983-85, Stanford University School of Medicine, Resident, General Surgery
1988-90, Stanford University School of Medicine, Resident, General Surgery
1990-91, Stanford University School of Medicine, Chief Resident, General Surgery
1991-93, Stanford University, M.B.A.
Board Certifications
American Board of Surgery - General Surgery - 1992
Collaboration Interests
I am interested in:
- policy change
Clinical Expertise
DCIS (Ductal Carcinoma in situ)
Inflammatory Breast Cancer
Invasive Breast Cancer
LCIS (Lobular Carcinoma in situ)
Lumpectomy/Partial Mastectomy
Lymphadenectomy
Mastectomy
Recurrent Breast Cancer
Sentinel Lymph Node Biopsy
Wire Localization Surgery
Clinical Trials
- MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles (NCT03053193)Related Conditions: Breast Cancer| Start Date: | End Date:
- I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer (NCT01042379)Related Conditions: Breast Cancer, Breast Tumor, Angiosarcoma, Triple-Negative Breast Cancer, HER2, Hormone Receptor Negative Tumor, Neoplasms| Start Date: | End Date:
- Related Conditions: COVID-19, Respiratory Distress Syndrome| Start Date: | End Date:
- Related Conditions: Breast Cancer, Menopause, Hot Flashes| Start Date: | End Date:
- Related Conditions: Breast Cancer, Cancer, General| Start Date: | End Date:
- Related Conditions: Carcinoma, Intraductal, Noninfiltrating, Immunotherapy| Start Date: | End Date:
- Related Conditions: Breast Cancer| Start Date: | End Date:
- Diagnostic Procedures in Women With Locally Advanced Breast Cancer Who Are Receiving Chemotherapy Before Breast Cancer Surgery (NCT00033397)Related Conditions: Breast Cancer| Start Date: | End Date:
- Effect of Fluvastatin on Biomarkers in Women Who Are Undergoing Surgery for Ductal Carcinoma In Situ or Stage I Breast Cancer (NCT00416403)Related Conditions: Breast Cancer| Start Date: | End Date:
- Postoperative Pain Control With Fentanyl Patch in Patients Undergoing Mastectomy and TRAM or DIEP Flap Reconstruction (NCT01258296)Related Conditions: Postoperative Pain| Start Date: | End Date:
- Related Conditions: Breast Cancer| Start Date: | End Date:
- Statins and Breast Cancer Biomarkers (NCT00914017)Related Conditions: Breast Cancer| Start Date:
Program Affiliations
- UCSF Center of Excellence for Breast Cancer Care
- UCSF Breast Care Center
- UCSF Helen Diller Comprehensive Cancer Center
Translational Co-Lead: Dr. Laura Esserman, is internationally recognized for her leadership of the ground-breaking I-SPY2 clinical trial and as an advocate for de-escalation of treatment for DCIS, and the initiation of the virtual preference pragmatic personalized screening trial (WISDOM) seeking to personalize the approach to screening. Her work in breast cancer spans the spectrum from public policy issues to basic science and the impact of both on the delivery of clinical care. Dr. Esserman has mentored 36 post-doctoral or clinical fellows during her career. She developed and runs a post-baccalaureate program that has trained 123 students over the past 15 years, most of whom have gone on to careers in medicine.
Dr. Esserman’s broad research interests provide exceptional opportunities for multidisciplinary training across the three themes, through clinical trials and biomarker studies on screening, prevention and treatment of breast cancer, many of which focus on improving healthcare value. Another fundamental and scalable effort is the implementation of systems to integrate care and research.
In the News
Grants and Funding
- Surgical Oncology Training Grant | NIH | 2020-07-15 - 2025-06-30 | Role: Principal Investigator
- Extending the Diversity, Reach, and Generalizability of the WISDOM Study | NIH | 2020-03-01 - 2025-02-28 | Role: Principal Investigator
- I-SPY2 +: Evolving the I-SPY 2 TRIAL to include MRI-directed, adaptive sequential treatment to optimize breast cancer outcomes | NIH | 2017-09-08 - 2022-08-31 | Role: Principal Investigator
- Elucidating the molecular and contextual basis for IDLE ultralow risk lesions and the tumor immune microenvironment of high risk in situ and invasive breast cancers | NIH | 2015-09-16 - 2021-08-31 | Role: Principal Investigator
- Modeling the Impact of Targeted Therapy Based on Breast Cancer Subtypes | NIH | 2014-09-18 - 2020-08-31 | Role: Principal Investigator
- Integrated Biomarkers to Characterize Breast Cancer Risk | NIH | 2004-09-20 - 2011-06-30 | Role: Principal Investigator
Research Interests
- BRCA1 Protein
- BRCA2 Protein
- Breast Diseases
- Breast Neoplasms
- Male
- Mastectomy
- Segmental
- Ultrasonography
- Mammary
- Cancer Vaccines
- Genes
- Tumor Suppressor
- Oncogenes
- Precancerous Conditions
- Infiltrating Duct Carcinoma
- Intraductal Carcinoma
- Noninfiltrating Carcinoma Lobular
Publications
- Immune and Growth Factor Signaling Pathways Are Associated with Pathologic Complete Response to an Anti-Type I Insulin-like Growth Factor Receptor Regimen in Patients with Breast Cancer.| | PubMed PubMed
- Integrating breast cancer polygenic risk scores at scale in the WISDOM Study: a national randomized personalized screening trial.| | PubMed PubMed
- Organoid-evaluable clinical biomarkers predict drug responses and guide new breast cancer therapies.| | PubMed PubMed
- Integration of Gene Expression and Digital Histology to Predict Treatment-Specific Responses in Breast Cancer.| | PubMed PubMed
- Impact of Time to Surgery Post Neoadjuvant Chemotherapy on Breast Cancer Outcomes: A Retrospective Study of Patients Enrolled in the I-SPY 2 Clinical Trial.| | PubMed PubMed
- Detection of serum HER2 in patients treated with neratinib or trastuzumab: analysis of the I-SPY Trial.| | PubMed PubMed
- Impact of Neoadjuvant Chemotherapy on Surgical Outcomes and Conversion to Node-Negativity in Invasive Lobular Breast Cancer: Analysis of Molecularly High-Risk Tumors by Histologic Subtype on the I-SPY2 Clinical Trial.| | PubMed PubMed
- Disparities in the Surgical Management of the Axilla by Self-Identified Race in the Multicenter Neoadjuvant I-SPY2 Trial.| | PubMed PubMed
- Pilot Study: Investigating the Local Breast Microbiome in Implant-based Breast Reconstruction Using 16S rRNA Sequencing.| | PubMed PubMed
- Peripheral blood gene expression signatures of systemic immunity predict tumor microenvironment biology and therapeutic response in breast cancer.| | PubMed PubMed
- Translating risk-based breast cancer screening to limited-resource settings.| | PubMed PubMed
- Insights from a multi-institutional registry show duration of endocrine treatment for DCIS impacts second events.| | PubMed PubMed
- Socioeconomic status impacts tumor biology, treatment, and outcomes in over 200,000 patients with invasive lobular carcinoma of the breast: an analysis of the National Cancer Database.| | PubMed PubMed
- Combined prognostic impact of initial clinical stage and residual cancer burden after neoadjuvant systemic therapy in triple-negative and HER2-positive breast cancer: an analysis of the I-SPY2 randomized clinical trial.| | PubMed PubMed
- Immune Subtyping Identifies Patients With Hormone Receptor-Positive Early-Stage Breast Cancer Who Respond to Neoadjuvant Immunotherapy (IO): Results From Five IO Arms of the I-SPY2 Trial.| | PubMed PubMed
- Pilot Study: A Prospective Placebo-control Trial Evaluating Topical Tranexamic Acid in Postmastectomy Breast Reconstruction.| | PubMed PubMed
- Differential long-term tamoxifen therapy benefit by menopausal status in breast cancer patients: secondary analysis of a controlled randomized clinical trial.| | PubMed PubMed
- Impact of IVF Restriction on Patients With Cancer and Surgeons.| | PubMed PubMed
- Intratumoral Injection of mRNA-2752 and Pembrolizumab for High-Risk Ductal Carcinoma In Situ: A Phase 1 Nonrandomized Clinical Trial.| | PubMed PubMed
- MRI-Based Model for Personalizing Neoadjuvant Treatment in Breast Cancer.| | PubMed PubMed
- National yearly cost of breast cancer screening in the USA and projected cost of advocated guidelines: a simulation study with life table modelling.| | PubMed PubMed
- A pooled analysis evaluating prognostic significance of Residual Cancer Burden in invasive lobular breast cancer.| | PubMed PubMed
- Oncologic Outcomes with De-Escalation of Axillary Surgery After Neoadjuvant Chemotherapy for Breast Cancer: Results from > 1500 Patients on the I-SPY2 Clinical Trial.| | PubMed PubMed
- Implantation of engineered adipocytes suppresses tumor progression in cancer models.| | PubMed PubMed
- Bilateral Mastectomy vs Lumpectomy and Breast Cancer Mortality Risk.| | PubMed PubMed
- Hormone Receptor-Positive HER2-Negative/MammaPrint High-2 Breast Cancers Closely Resemble Triple-Negative Breast Cancers.| | PubMed PubMed
- Correction: A roadmap to reduce the incidence and mortality of breast cancer by rethinking our approach to women's health.| | PubMed PubMed
- Implementation and impact of an electronic patient reported outcomes system in a phase II multi-site adaptive platform clinical trial for early-stage breast cancer.| | PubMed PubMed
- Anti-CD14 treatment in patients with severe COVID-19: Clinical and biological effects in a Phase 2 randomized open-label adaptive platform clinical trial.| | PubMed PubMed
- Pexidartinib and standard neoadjuvant therapy in the adaptively randomized I-SPY2 trial for early breast cancer.| | PubMed PubMed
- Relationship Between Perceived COVID-19 Risk and Change in Perceived Breast Cancer Risk: Prospective Observational Study.| | PubMed PubMed
- Tumor Morphology for Prediction of Poor Responses Early in Neoadjuvant Chemotherapy for Breast Cancer: A Multicenter Retrospective Study.| | PubMed PubMed
- A roadmap to reduce the incidence and mortality of breast cancer by rethinking our approach to women's health.| | PubMed PubMed
- Balancing risks of surgical complications and positive margins for patients with invasive lobular carcinoma of the breast and elevated BMI: An institutional cohort study.| | PubMed PubMed
- Multi-platform biomarkers of response to an immune checkpoint inhibitor in the neoadjuvant I-SPY 2 trial for early-stage breast cancer.| | PubMed PubMed
- Screening Mammography for 40-Year-Old Women-Whose Decision?| | PubMed PubMed
- Gut and oral microbial compositional differences in women with breast cancer, women with ductal carcinoma in situ, and healthy women.| | PubMed PubMed
- Pathologic complete response (pCR) rates for patients with HR+/HER2- high-risk, early-stage breast cancer (EBC) by clinical and molecular features in the phase II I-SPY2 clinical trial.| | PubMed PubMed
- Validation study of risk-reduction activities after personalized breast cancer education tool in the WISDOM study.| | PubMed PubMed
- Regional lymph node changes on breast MRI in patients with early-stage breast cancer receiving neoadjuvant chemo-immunotherapy.| | PubMed PubMed
- Overcoming challenges in conducting early phase breast cancer prevention trials: Bazedoxifene and conjugated estrogens vs waitlist control.| | PubMed PubMed
- Datopotamab-deruxtecan in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial.| | PubMed PubMed
- Datopotamab-deruxtecan plus durvalumab in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial.| | PubMed PubMed
- Modernizing the Data Infrastructure for Clinical Research to Meet Evolving Demands for Evidence.| | PubMed PubMed
- Magnetic resonance imaging insights from active surveillance of women with ductal carcinoma in situ.| | PubMed PubMed
- Clipping the Positive Lymph Node in Patients with Clinically Node Positive Breast Cancer Treated with Neoadjuvant Chemotherapy: Impact on Axillary Surgery in the ISPY-2 Clinical Trial.| | PubMed PubMed
- Internal Mammary Lymphadenopathy Does Not Impact Oncologic Outcomes in Patients Treated with Neoadjuvant Chemotherapy: Results from the I-SPY2 Clinical Trial.| | PubMed PubMed
- Cell-free DNA Concentration as a Biomarker of Response and Recurrence in HER2-Negative Breast Cancer Receiving Neoadjuvant Chemotherapy.| | PubMed PubMed
- Tumor microenvironmental determinants of high-risk DCIS progression.| | PubMed PubMed
- Reproductive rights in the United States: acquiescence is not a strategy.| | PubMed PubMed
- Epithelial Expressed B7-H4 Drives Differential Immunotherapy Response in Murine and Human Breast Cancer.| | PubMed PubMed
- Neoadjuvant Chemotherapy and Immunotherapy for Estrogen Receptor-Positive Human Epidermal Growth Factor 2-Negative Breast Cancer.| | PubMed PubMed
- RE: Supplemental magnetic resonance imaging plus mammography compared with magnetic resonance imaging or mammography by extent of breast density.| | PubMed PubMed
- Incidence and Mitigation of Corneal Pseudomicrocysts Induced by Antibody-Drug Conjugates (ADCs).| | PubMed PubMed
- Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers.| | PubMed PubMed
- 18F-FDG Dedicated Breast PET Complementary to Breast MRI for Evaluating Early Response to Neoadjuvant Chemotherapy.| | PubMed PubMed
- Circulating tumor cells in early lobular versus ductal breast cancer and their associations with prognosis.| | PubMed PubMed
- Novel subtypes of severe COVID-19 respiratory failure based on biological heterogeneity: a secondary analysis of a randomized controlled trial.| | PubMed PubMed
- Neoadjuvant Trebananib plus Paclitaxel-based Chemotherapy for Stage II/III Breast Cancer in the Adaptively Randomized I-SPY2 Trial-Efficacy and Biomarker Discovery.| | PubMed PubMed
- Duration of Endocrine Treatment for DCIS impacts second events: Insights from a large cohort of cases at two academic medical centers.| | PubMed PubMed
- Characterizing attitudes related to future child-bearing in young women diagnosed with early-stage breast cancer.| | PubMed PubMed
- Precision Oncology in Breast Cancer Surgery.| | PubMed PubMed
- Protein signaling and drug target activation signatures to guide therapy prioritization: Therapeutic resistance and sensitivity in the I-SPY 2 Trial.| | PubMed PubMed
- Race, Gene Expression Signatures, and Clinical Outcomes of Patients With High-Risk Early Breast Cancer.| | PubMed PubMed
- Concordance between patient-reported and physician-documented comorbidities and symptoms among Stage 4 breast cancer patients.| | PubMed PubMed
- The impact of histologic subtype on primary site surgery in the management of metastatic lobular versus ductal breast cancer: a population based study from the National Cancer Database (NCDB).| | PubMed PubMed
- Pituitary adenoma or neuroendocrine tumour: the need for an integrated prognostic classification.| | PubMed PubMed
- Area Deprivation Index in Patients with Invasive Lobular Carcinoma of the Breast: Associations with Tumor Characteristics and Outcomes.| | PubMed PubMed
- Early Ascertainment of Breast Cancer Diagnoses Comparing Self-Reported Questionnaires and Electronic Health Record Data Warehouse: The WISDOM Study.| | PubMed PubMed
- The impact of histologic subtype on primary site surgery in the management of metastatic lobular versus ductal breast cancer: a population based study from the National Cancer Database.| | PubMed PubMed
- Predictors of Early Versus Late Recurrence in Invasive Lobular Carcinoma of the Breast: Impact of Local and Systemic Therapy.| | PubMed PubMed
- Effect of Longitudinal Variation in Tumor Volume Estimation for MRI-guided Personalization of Breast Cancer Neoadjuvant Treatment.| | PubMed PubMed
- A Truly Pro-Life Position Requires Access to Reproductive Health Care.| | PubMed PubMed
- Changes in Surgical Management of the Axilla Over 11 Years - Report on More Than 1500 Breast Cancer Patients Treated with Neoadjuvant Chemotherapy on the Prospective I-SPY2 Trial.| | PubMed PubMed
- Breast Conservation Surgery and Mastectomy Have Similar Locoregional Recurrence After Neoadjuvant Chemotherapy: Results From 1462 Patients on the Prospective, Randomized I-SPY2 Trial.| | PubMed PubMed
- Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes.| | PubMed PubMed
- Comparison of Mammography AI Algorithms with a Clinical Risk Model for 5-year Breast Cancer Risk Prediction: An Observational Study.| | PubMed PubMed
- Prognostic Significance of Residual Ductal Carcinoma In Situ After Complete Response of Invasive Breast Cancer to Neoadjuvant Therapy-Reply.| | PubMed PubMed
- Development and testing of a polygenic risk score for breast cancer aggressiveness.| | PubMed PubMed
- Validation Study on Risk-Reduction Activities after Exposure to a Personalized Breast Cancer Risk-Assessment Education Tool in High-Risk Women in the WISDOM Study.| | PubMed PubMed
- Clinical significance and biology of circulating tumor DNA in high-risk early-stage HER2-negative breast cancer receiving neoadjuvant chemotherapy.| | PubMed PubMed
- Time to Surgery in Breast Cancer-Is Faster Always Better?| | PubMed PubMed
- Association of baseline ROR1 and ROR2 gene expression with clinical outcomes in the I-SPY2 neoadjuvant breast cancer trial.| | PubMed PubMed
- Guiding principles for the responsible development of artificial intelligence tools for healthcare.| | PubMed PubMed
- Radiomic tumor phenotypes augment molecular profiling in predicting recurrence free survival after breast neoadjuvant chemotherapy.| | PubMed PubMed
- Implantation of engineered adipocytes that outcompete tumors for resources suppresses cancer progression.| | PubMed PubMed
- When Less Can Be More: How the 10-Year Updated Results From the Randomized Controlled AMAROS Trial Should Affect Axillary Management in the Setting of a Positive Node.| | PubMed PubMed
- Expanding Candidacy for Nipple-sparing Mastectomy in Women with Large or Ptotic Breasts: Staged Reconstruction Outcomes.| | PubMed PubMed
- Outcomes and clinicopathologic characteristics associated with disseminated tumor cells in bone marrow after neoadjuvant chemotherapy in high-risk early stage breast cancer: the I-SPY SURMOUNT study.| | PubMed PubMed
- Identifying Good Candidates for Active Surveillance of Ductal Carcinoma In Situ: Insights from a Large Neoadjuvant Endocrine Therapy Cohort.| | PubMed PubMed
- Safety and efficacy of HSP90 inhibitor ganetespib for neoadjuvant treatment of stage II/III breast cancer.| | PubMed PubMed
- Author Correction: Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.| | PubMed PubMed
- Association of Residual Ductal Carcinoma In Situ With Breast Cancer Recurrence in the Neoadjuvant I-SPY2 Trial.| | PubMed PubMed
- Informed consent process in the ISPY COVID trial is ethically acceptable.| | PubMed PubMed
- Focal Therapy for Prostate Cancer: Evolutionary Parallels to Breast Cancer Treatment.| | PubMed PubMed
- Diffusion-Weighted MRI for Predicting Pathologic Complete Response in Neoadjuvant Immunotherapy.| | PubMed PubMed
- Twenty-Year Benefit From Adjuvant Goserelin and Tamoxifen in Premenopausal Patients With Breast Cancer in a Controlled Randomized Clinical Trial.| | PubMed PubMed
- Validation of the 70-gene signature test (MammaPrint) to identify patients with breast cancer aged ≥ 70 years with ultralow risk of distant recurrence: A population-based cohort study.| | PubMed PubMed
- Why It Is Time to Challenge Entrenched Beliefs About Breast Cancer Screening.| | PubMed PubMed
- Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.| | PubMed PubMed
- Optimizing hormone therapy for breast cancer: Translating gains to the early-stage setting.| | PubMed PubMed
- I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations.| | PubMed PubMed
- Redefining breast cancer subtypes to guide treatment prioritization and maximize response: Predictive biomarkers across 10 cancer therapies.| | PubMed PubMed
- Treatment Efficacy Score-continuous residual cancer burden-based metric to compare neoadjuvant chemotherapy efficacy between randomized trial arms in breast cancer trials.| | PubMed PubMed
- Effect of Inter-Reader Variability on Diffusion-Weighted MRI Apparent Diffusion Coefficient Measurements and Prediction of Pathologic Complete Response for Breast Cancer.| | PubMed PubMed
- Association of Residual Cancer Burden After Neoadjuvant Therapy and Event-Free Survival in Breast Cancer-Reply.| | PubMed PubMed
- Clinical and molecular characteristics of estrogen receptor-positive ultralow risk breast cancer tumors identified by the 70-gene signature.| | PubMed PubMed
- Survivorship after neoadjuvant chemotherapy - Authors' reply.| | PubMed PubMed
- Evaluation of the Pathways for Survivors Program to Address Breast Cancer Survivorship-Associated Distress: Survey Study.| | PubMed PubMed
- Outcome of Patients With an Ultralow-Risk 70-Gene Signature in the MINDACT Trial.| | PubMed PubMed
- The breast pre-cancer atlas illustrates the molecular and micro-environmental diversity of ductal carcinoma in situ.| | PubMed PubMed
- The incidence of discordant clinical and genomic risk in patients with invasive lobular or ductal carcinoma of the breast: a National Cancer Database Study.| | PubMed PubMed
- Residual cancer burden after neoadjuvant chemotherapy and long-term survival outcomes in breast cancer: a multicentre pooled analysis of 5161 patients.| | PubMed PubMed
- A case-case analysis of women with breast cancer: predictors of interval vs screen-detected cancer.| | PubMed PubMed
- Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2+ breast cancer in the adaptively randomized I-SPY2 trial.| | PubMed PubMed
- RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer.| | PubMed PubMed
- Assessment of Residual Cancer Burden and Event-Free Survival in Neoadjuvant Treatment for High-risk Breast Cancer: An Analysis of Data From the I-SPY2 Randomized Clinical Trial.| | PubMed PubMed
- Decreased enrollment in breast cancer trials by histologic subtype: does invasive lobular carcinoma resist RECIST?| | PubMed PubMed
- Ganitumab and metformin plus standard neoadjuvant therapy in stage 2/3 breast cancer.| | PubMed PubMed
- Pre-Appointment Nurse Navigation: Patient-Centered Findings From a Survey of Patients With Breast Cancer.| | PubMed PubMed
- Health screening needs independent regular re-evaluation.| | PubMed PubMed
- Trigger point injection for post-mastectomy pain: a simple intervention with high rate of long-term relief.| | PubMed PubMed
- The WISDOM study: a new approach to screening can and should be tested.| | PubMed PubMed
- The use of neoadjuvant therapy to further personalize breast cancer treatment.| | PubMed PubMed
- Breast MRI during Neoadjuvant Chemotherapy: Lack of Background Parenchymal Enhancement Suppression and Inferior Treatment Response.| | PubMed PubMed
- Elevated risk thresholds predict endocrine risk-reducing medication use in the Athena screening registry.| | PubMed PubMed
- Authors' Reply: To the Letter to the Editor by Groheux et al.| | PubMed PubMed
- Advancing precision medicine for acute respiratory distress syndrome.| | PubMed PubMed
- Development and pilot of an online, personalized risk assessment tool for a breast cancer precision medicine trial.| | PubMed PubMed
- Durvalumab with olaparib and paclitaxel for high-risk HER2-negative stage II/III breast cancer: Results from the adaptively randomized I-SPY2 trial.| | PubMed PubMed
- Positive margins after mastectomy in patients with invasive lobular carcinoma of the breast: Incidence and management strategies.| | PubMed PubMed
- PRoBE the cloud toolkit: finding the best biomarkers of drug response within a breast cancer clinical trial.| | PubMed PubMed
- Assessment of 25-Year Survival of Women With Estrogen Receptor-Positive/ERBB2-Negative Breast Cancer Treated With and Without Tamoxifen Therapy: A Secondary Analysis of Data From the Stockholm Tamoxifen Randomized Clinical Trial.| | PubMed PubMed
- Modulation of the immune microenvironment of high-risk ductal carcinoma in situ by intralesional pembrolizumab injection.| | PubMed PubMed
- Incorporation of Patient-Reported Outcomes Measurement Information System to assess quality of life among patients with breast cancer initiating care at an academic center.| | PubMed PubMed
- Mask-Guided Convolutional Neural Network for Breast Tumor Prognostic Outcome Prediction on 3D DCE-MR Images.| | PubMed PubMed
- Circulating tumor DNA and magnetic resonance imaging to predict neoadjuvant chemotherapy response and recurrence risk.| | PubMed PubMed
- Accuracy of breast MRI in evaluating nodal status after neoadjuvant therapy in invasive lobular carcinoma.| | PubMed PubMed
- Predicted sensitivity to endocrine therapy for stage II-III hormone receptor-positive and HER2-negative (HR+/HER2-) breast cancer before chemo-endocrine therapy.| | PubMed PubMed
- Characterizing the Tumor Immune Microenvironment with Tyramide-Based Multiplex Immunofluorescence.| | PubMed PubMed
- Contralateral prophylactic mastectomy: A narrative review of the evidence and acceptability.| | PubMed PubMed
- A world-wide survey on kidney transplantation practices in breast cancer survivors: The need for new management guidelines.| | PubMed PubMed
- Characterization of Oligometastatic Disease in a Real-World Nationwide Cohort of 3447 Patients With de Novo Metastatic Breast Cancer.| | PubMed PubMed
- Accuracy of sentinel lymph node biopsy in invasive lobular carcinoma of the breast: Factors associated with false negatives.| | PubMed PubMed
- MCM3 upregulation confers endocrine resistance in breast cancer and is a predictive marker of diminished tamoxifen benefit.| | PubMed PubMed
- Prime Time for Consultation Audio Recordings: Supporting Shared Decision Making During and After the COVID-19 Era.| | PubMed PubMed
- Evaluation of primary breast cancers using dedicated breast PET and whole-body PET.| | PubMed PubMed
- Predicting breast cancer response to neoadjuvant treatment using multi-feature MRI: results from the I-SPY 2 TRIAL.| | PubMed PubMed
- Circulating tumor DNA in neoadjuvant-treated breast cancer reflects response and survival.| | PubMed PubMed
- Mutational profiling of micro-dissected pre-malignant lesions from archived specimens.| | PubMed PubMed
- Use of 18F-FDG PET/CT as an Initial Staging Procedure for Stage II-III Breast Cancer: A Multicenter Value Analysis.| | PubMed PubMed
- Publisher Correction: Personalized early detection and prevention of breast cancer: ENVISION consensus statement.| | PubMed PubMed
- The quality of life index: a pilot study integrating treatment efficacy and quality of life in oncology.| | PubMed PubMed
- The Evolution of Our Understanding of the Biology of Cancer Is the Key to Avoiding Overdiagnosis and Overtreatment.| | PubMed PubMed
- Oncological Outcomes of Total Skin-Sparing Mastectomy for Invasive Lobular Carcinoma of the Breast: A 20-Year Institutional Experience.| | PubMed PubMed
- Mechanism of action biomarkers predicting response to AKT inhibition in the I-SPY 2 breast cancer trial.| | PubMed PubMed
- Association of Event-Free and Distant Recurrence-Free Survival With Individual-Level Pathologic Complete Response in Neoadjuvant Treatment of Stages 2 and 3 Breast Cancer: Three-Year Follow-up Analysis for the I-SPY2 Adaptively Randomized Clinical Trial.| | PubMed PubMed
- Cost-effectiveness of consensus guideline based management of pancreatic cysts: The sensitivity and specificity required for guidelines to be cost-effective.| | PubMed PubMed
- Predictive Value of Breast MRI Background Parenchymal Enhancement for Neoadjuvant Treatment Response among HER2- Patients.| | PubMed PubMed
- Evaluating the impact of axillary dissection on recurrence-free survival by extent of nodal disease in invasive lobular carcinoma of the breast.| | PubMed PubMed
- Breast conservation therapy versus mastectomy in the surgical management of invasive lobular carcinoma measuring 4 cm or greater.| | PubMed PubMed
- Personalized early detection and prevention of breast cancer: ENVISION consensus statement.| | PubMed PubMed
- Current Landscape of Breast Cancer Imaging and Potential Quantitative Imaging Markers of Response in ER-Positive Breast Cancers Treated with Neoadjuvant Therapy.| | PubMed PubMed
- Comparison of Segmentation Methods in Assessing Background Parenchymal Enhancement as a Biomarker for Response to Neoadjuvant Therapy.| | PubMed PubMed
- Impact of MRI Protocol Adherence on Prediction of Pathological Complete Response in the I-SPY 2 Neoadjuvant Breast Cancer Trial.| | PubMed PubMed
- Tumor Sphericity Predicts Response in Neoadjuvant Chemotherapy for Invasive Breast Cancer.| | PubMed PubMed
- Effect of Pembrolizumab Plus Neoadjuvant Chemotherapy on Pathologic Complete Response in Women With Early-Stage Breast Cancer: An Analysis of the Ongoing Phase 2 Adaptively Randomized I-SPY2 Trial.| | PubMed PubMed
- Personalization of Treatment is the Way Forward in Care and Trials.| | PubMed PubMed
- Mitotic score and pleomorphic histology in invasive lobular carcinoma of the breast: impact on disease-free survival.| | PubMed PubMed
- Response to Carter et al.| | PubMed PubMed
- Phase II Single-Arm Study of Preoperative Letrozole for Estrogen Receptor-Positive Postmenopausal Ductal Carcinoma In Situ: CALGB 40903 (Alliance).| | PubMed PubMed
- We need more evidence to answer questions about screening.| | PubMed PubMed
- Abdominal Imaging of Pancreatic Cysts and Cyst-Associated Pancreatic Cancer in BRCA1/2 Mutation Carriers: A Retrospective Cross-Sectional Study.| | PubMed PubMed
- Success rates of re-excision after positive margins for invasive lobular carcinoma of the breast.| | PubMed PubMed
- Assessment of Long-term Distant Recurrence-Free Survival Associated With Tamoxifen Therapy in Postmenopausal Patients With Luminal A or Luminal B Breast Cancer.| | PubMed PubMed
- A case report of vanishing bile duct syndrome after exposure to pexidartinib (PLX3397) and paclitaxel.| | PubMed PubMed
- Synchronous Detection of Circulating Tumor Cells in Blood and Disseminated Tumor Cells in Bone Marrow Predicts Adverse Outcome in Early Breast Cancer.| | PubMed PubMed
- Fitbit Usage in Patients With Breast Cancer Undergoing Chemotherapy.| | PubMed PubMed
- Additive value of diffusion-weighted MRI in the I-SPY 2 TRIAL.| | PubMed PubMed
- Initial experience of dedicated breast PET imaging of ER+ breast cancers using [F-18]fluoroestradiol.| | PubMed PubMed
- A response to "Personalised medicine and population health: breast and ovarian cancer".| | PubMed PubMed
- MK-2206 and Standard Neoadjuvant Chemotherapy Improves Response in Patients With Human Epidermal Growth Factor Receptor 2-Positive and/or Hormone Receptor-Negative Breast Cancers in the I-SPY 2 Trial.| | PubMed PubMed
- Should we rename low risk cancers?| | PubMed PubMed
- Evaluation of National Comprehensive Cancer Network guideline-based Tool for Risk Assessment for breast and ovarian Cancer (N-TRAC): A patient-reported survey for genetic high-risk assessment for breast and ovarian cancers in women.| | PubMed PubMed
- The WISDOM Personalized Breast Cancer Screening Trial: Simulation Study to Assess Potential Bias and Analytic Approaches.| | PubMed PubMed
- Erratum: Author Correction: Surgical Standards for Management of the Axilla in Breast Cancer Clinical Trials with Pathological Complete Response Endpoint.| | PubMed PubMed
- Functional Status and Survival After Breast Cancer Surgery in Nursing Home Residents.| | PubMed PubMed
- Precision risk-based screening might maximize benefit and minimize harm.| | PubMed PubMed
- Test-retest repeatability and reproducibility of ADC measures by breast DWI: Results from the ACRIN 6698 trial.| | PubMed PubMed
- Genomic and expression profiling reveal molecular heterogeneity of disseminated tumor cells in bone marrow of early breast cancer.| | PubMed PubMed
- Diffusion-weighted MRI Findings Predict Pathologic Response in Neoadjuvant Treatment of Breast Cancer: The ACRIN 6698 Multicenter Trial.| | PubMed PubMed
- Surgical Standards for Management of the Axilla in Breast Cancer Clinical Trials with Pathological Complete Response Endpoint.| | PubMed PubMed
- Evaluation of the HER/PI3K/AKT Family Signaling Network as a Predictive Biomarker of Pathologic Complete Response for Patients With Breast Cancer Treated With Neratinib in the I-SPY 2 TRIAL.| | PubMed PubMed
- Exploration of PET and MRI radiomic features for decoding breast cancer phenotypes and prognosis.| | PubMed PubMed
- Breast Conservation and Negative Margins in Invasive Lobular Carcinoma: The Impact of Oncoplastic Surgery and Shave Margins in 358 Patients.| | PubMed PubMed
- The DigniCap Scalp Cooling System and its use in the treatment of chemotherapy-induced alopecia.| | PubMed PubMed
- Intratumor Heterogeneity of the Estrogen Receptor and the Long-term Risk of Fatal Breast Cancer.| | PubMed PubMed
- Circulating Tumor Cells in Breast Cancer Patients Treated by Neoadjuvant Chemotherapy: A Meta-analysis.| | PubMed PubMed
- Systematic review of the impact of breast-conserving surgery on cancer outcomes of multiple ipsilateral breast cancers.| | PubMed PubMed
- MRI, Clinical Examination, and Mammography for Preoperative Assessment of Residual Disease and Pathologic Complete Response After Neoadjuvant Chemotherapy for Breast Cancer: ACRIN 6657 Trial.| | PubMed PubMed
- Improved analgesia and reduced post-operative nausea and vomiting after implementation of an enhanced recovery after surgery (ERAS) pathway for total mastectomy.| | PubMed PubMed
- Initial Clinical Experience With an Inducible Magnetic Seed System for Preoperative Breast Lesion Localization.| | PubMed PubMed
- Complications After Total Skin-Sparing Mastectomy and Expander-Implant Reconstruction: Effects of Radiation Therapy on the Stages of Reconstruction.| | PubMed PubMed
- Features of MRI stromal enhancement with neoadjuvant chemotherapy: a subgroup analysis of the ACRIN 6657/I-SPY TRIAL.| | PubMed PubMed
- Rapid detection of BRCA1/2 recurrent mutations in Chinese breast and ovarian cancer patients with multiplex SNaPshot genotyping panels.| | PubMed PubMed
- Mechanisms of Resistance to Neoadjuvant Chemotherapy in Breast Cancer.| | PubMed PubMed
- Use of Molecular Tools to Identify Patients With Indolent Breast Cancers With Ultralow Risk Over 2 Decades.| | PubMed PubMed
- The value of embedding: integrated palliative care for patients with metastatic breast cancer.| | PubMed PubMed
- Registry study to assess hair loss prevention with the Penguin Cold Cap in breast cancer patients receiving chemotherapy.| | PubMed PubMed
- The WISDOM Study: breaking the deadlock in the breast cancer screening debate.| | PubMed PubMed
- Heterogeneous drug penetrance of veliparib and carboplatin measured in triple negative breast tumors.| | PubMed PubMed
- DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial.| | PubMed PubMed
- Tamoxifen therapy benefit for patients with 70-gene signature high and low risk.| | PubMed PubMed
- Erratum to: Fertility preservation with ovarian stimulation and time to treatment in women with stage II-III breast cancer receiving neoadjuvant therapy.| | PubMed PubMed
- Indications for Postmastectomy Radiation After Neoadjuvant Chemotherapy in ypN0 and ypN1-3 Axillary Node-Positive Women.| | PubMed PubMed
- Comparison of residual cancer burden, American Joint Committee on Cancer staging and pathologic complete response in breast cancer after neoadjuvant chemotherapy: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).| | PubMed PubMed
- Receptor activator of nuclear factor kappa B (RANK) expression in primary breast cancer correlates with recurrence-free survival and development of bone metastases in I-SPY1 (CALGB 150007/150012; ACRIN 6657).| | PubMed PubMed
- Fertility preservation with ovarian stimulation and time to treatment in women with stage II-III breast cancer receiving neoadjuvant therapy.| | PubMed PubMed
- Vaginal Testosterone Cream vs Estradiol Vaginal Ring for Vaginal Dryness or Decreased Libido in Women Receiving Aromatase Inhibitors for Early-Stage Breast Cancer: A Randomized Clinical Trial.| | PubMed PubMed
- Association Between Use of a Scalp Cooling Device and Alopecia After Chemotherapy for Breast Cancer.| | PubMed PubMed
- Precision surgery and avoiding over-treatment.| | PubMed PubMed
- Breast Cancer Screening in the Precision Medicine Era: Risk-Based Screening in a Population-Based Trial.| | PubMed PubMed
- Ki67 Proliferation Index as a Tool for Chemotherapy Decisions During and After Neoadjuvant Aromatase Inhibitor Treatment of Breast Cancer: Results From the American College of Surgeons Oncology Group Z1031 Trial (Alliance).| | PubMed PubMed
- Dedicated Breast Positron Emission Tomography for the Evaluation of Early Response to Neoadjuvant Chemotherapy in Breast Cancer.| | PubMed PubMed
- MR spectroscopy of breast cancer for assessing early treatment response: Results from the ACRIN 6657 MRS trial.| | PubMed PubMed
- Do Prolonged Prophylactic Antibiotics Reduce the Incidence of Surgical-Site Infections in Immediate Prosthetic Breast Reconstruction?| | PubMed PubMed
- Effect of MR Imaging Contrast Thresholds on Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer Subtypes: A Subgroup Analysis of the ACRIN 6657/I-SPY 1 TRIAL.| | PubMed PubMed
- Co-expression modules identified from published immune signatures reveal five distinct immune subtypes in breast cancer.| | PubMed PubMed
- Characterizing the immune microenvironment in high-risk ductal carcinoma in situ of the breast.| | PubMed PubMed
- Adaptive Randomization of Neratinib in Early Breast Cancer.| | PubMed PubMed
- PIPELINEs: Creating Comparable Clinical Knowledge Efficiently by Linking Trial Platforms.| | PubMed PubMed
- The I-SPY approach to drug development.| | PubMed PubMed
- Laura Esserman and Ian Thompson Discuss Strategies for Screening and Treatment of Early-Stage Cancers, and How Clinicians Can Learn From Each Other's Experiences.| | PubMed PubMed
- The Novel Application of Genomic Profiling Assays to Shorten Inactive Status for Potential Kidney Transplant Recipients With Breast Cancer.| | PubMed PubMed
- Adaptive Randomization of Neratinib in Early Breast Cancer.| | PubMed PubMed
- Adaptive Randomization of Veliparib-Carboplatin Treatment in Breast Cancer.| | PubMed PubMed
- When Less Is Better, but Physicians Are Afraid Not to Intervene.| | PubMed PubMed
- Proteomic mapping of p53 immunogenicity in pancreatic, ovarian, and breast cancers.| | PubMed PubMed
- Outcomes Following Oncoplastic Reduction Mammoplasty: A Systematic Review.| | PubMed PubMed
- Population-based screening for cancer: hope and hype.| | PubMed PubMed
- When the Gold Standard Loses Its Luster, Perhaps It Is Time to Change Nomenclature.| | PubMed PubMed
- Treatment and Long-Term Risks for Patients With a Diagnosis of Ductal Carcinoma In Situ-Reply.| | PubMed PubMed
- Effect of Imaging Parameter Thresholds on MRI Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer Subtypes.| | PubMed PubMed
- A phase 1b study of the Akt-inhibitor MK-2206 in combination with weekly paclitaxel and trastuzumab in patients with advanced HER2-amplified solid tumor malignancies.| | PubMed PubMed
- Time for a randomised clinical trial evaluating breast conserving surgery compared to mastectomy in ipsilateral mutlifocal breast cancer (MFBC)?| | PubMed PubMed
- Detection of ductal carcinoma in situ and subsequent interval cancers.| | PubMed PubMed
- CLINICAL DECISIONS. Ductal Carcinoma In Situ.| | PubMed PubMed
- Less Is More: The Evolving Surgical Approach to Breast Cancer.| | PubMed PubMed
- Neoadjuvant as Future for Drug Development in Breast Cancer--Response.| | PubMed PubMed
- The Impact of Radiation Therapy, Lymph Node Dissection, and Hormonal Therapy on Outcomes of Tissue Expander-Implant Exchange in Prosthetic Breast Reconstruction.| | PubMed PubMed
- Tissue Expander Reconstruction After Total Skin-Sparing Mastectomy: Defining the Effects of Coverage Technique on Nipple/Areola Preservation.| | PubMed PubMed
- Sentinel Lymph Node Mapping in Post-Mastectomy Chest Wall Recurrences: Influence on Radiation Treatment Fields and Outcome.| | PubMed PubMed
- Neoadjuvant Chemotherapy for Breast Cancer: Functional Tumor Volume by MR Imaging Predicts Recurrence-free Survival-Results from the ACRIN 6657/CALGB 150007 I-SPY 1 TRIAL.| | PubMed PubMed
- Rethinking the Standard for Ductal Carcinoma In Situ Treatment.| | PubMed PubMed
- Negative Genetic Testing Does Not Deter Contralateral Prophylactic Mastectomy in Younger Patients with Greater Family Histories of Breast Cancer.| | PubMed PubMed
- Association of tamoxifen use and ovarian function in patients with invasive or pre-invasive breast cancer.| | PubMed PubMed
- Standardization of pathologic evaluation and reporting of postneoadjuvant specimens in clinical trials of breast cancer: recommendations from an international working group.| | PubMed PubMed
- How to use magnetic resonance imaging following neoadjuvant chemotherapy in locally advanced breast cancer.| | PubMed PubMed
- Expanding the Indications for Total Skin-Sparing Mastectomy: Is It Safe for Patients with Locally Advanced Disease?| | PubMed PubMed
- In Regard to Hepel and Wazer.| | PubMed PubMed
- Preventing Overdiagnosis and Overtreatment: Just the Next Step in the Evolution of Breast Cancer Care.| | PubMed PubMed
- Serial expression analysis of breast tumors during neoadjuvant chemotherapy reveals changes in cell cycle and immune pathways associated with recurrence and response.| | PubMed PubMed
- Tumor Involvement of the Nipple in Total Skin-Sparing Mastectomy: Strategies for Management.| | PubMed PubMed
- Coaching patients in the use of decision and communication aids: RE-AIM evaluation of a patient support program.| | PubMed PubMed
- Recommendations for standardized pathological characterization of residual disease for neoadjuvant clinical trials of breast cancer by the BIG-NABCG collaboration.| | PubMed PubMed
- Comparison of Mammographic Findings Following Oncoplastic Mammoplasty and Lumpectomy Without Reconstruction.| | PubMed PubMed
- Approaches to microvascular breast reconstruction after total skin-sparing mastectomy: a comparison of techniques.| | PubMed PubMed
- Rates of Reconstruction Failure in Patients Undergoing Immediate Reconstruction With Tissue Expanders and/or Implants and Postmastectomy Radiation Therapy.| | PubMed PubMed
- Pride, Prejudice, or Science: Attitudes Towards the Results of the TARGIT-A Trial of Targeted Intraoperative Radiation Therapy for Breast Cancer.| | PubMed PubMed
- The impact of breast mass on outcomes of total skin-sparing mastectomy and immediate tissue expander-based breast reconstruction.| | PubMed PubMed
- The Neoadjuvant Model Is Still the Future for Drug Development in Breast Cancer.| | PubMed PubMed
- Development, implementation, and initial evaluation of a foundational open interoperability standard for oncology treatment planning and summarization.| | PubMed PubMed
- Preoperative Breast Pain Predicts Persistent Breast Pain and Disability After Breast Cancer Surgery.| | PubMed PubMed
- Construction and analysis of the NCI-EDRN breast cancer reference set for circulating markers of disease.| | PubMed PubMed
- SIS.NET: a randomized controlled trial evaluating a web-based system for symptom management after treatment of breast cancer.| | PubMed PubMed
- Expression profiling of circulating tumor cells in metastatic breast cancer.| | PubMed PubMed
- Immediate implant-based breast reconstruction following total skin-sparing mastectomy: defining the risk of preoperative and postoperative radiation therapy for surgical outcomes.| | PubMed PubMed
- Aggregate cost of mammography screening in the United States.| | PubMed PubMed
- Randomized trial of drain antisepsis after mastectomy and immediate prosthetic breast reconstruction.| | PubMed PubMed
- Haste makes waste, but lack of urgency is opportunity lost.| | PubMed PubMed
- Impact of total skin-sparing mastectomy incision type on reconstructive complications following radiation therapy.| | PubMed PubMed
- Moving beyond the breast cancer screening debate.| | PubMed PubMed
- Total skin-sparing mastectomy and immediate breast reconstruction: an evolution of technique and assessment of outcomes.| | PubMed PubMed
- Immediate implant-based breast reconstruction following total skin-sparing mastectomy in women with a history of augmentation mammaplasty: assessing the safety profile.| | PubMed PubMed
- Imaging features of HER2 overexpression in breast cancer: a systematic review and meta-analysis.| | PubMed PubMed
- Addressing overdiagnosis and overtreatment in cancer: a prescription for change.| | PubMed PubMed
- Fifty years of age-based screening: time for a new risk-based screening approach.| | PubMed PubMed
- Local recurrence rates are low in high-risk neoadjuvant breast cancer in the I-SPY 1 Trial (CALGB 150007/150012; ACRIN 6657).| | PubMed PubMed
- Oncoplastic mammoplasty as a strategy for reducing reconstructive complications associated with postmastectomy radiation therapy.| | PubMed PubMed
- Patient-reported outcomes and satisfaction after total skin-sparing mastectomy and immediate expander-implant reconstruction.| | PubMed PubMed
- Accelerated approval for pertuzumab in the neoadjuvant setting: winds of change?| | PubMed PubMed
- Pretreatment vitamin D level and response to neoadjuvant chemotherapy in women with breast cancer on the I-SPY trial (CALGB 150007/150015/ACRIN6657).| | PubMed PubMed
- Setting a research agenda for ductal carcinoma in situ that meets the current need for change.| | PubMed PubMed
- Application of a decision analytic framework for adoption of clinical trial results: are the data regarding TARGIT-A IORT ready for prime time?| | PubMed PubMed
- Abstract 124: outcomes of total skin-sparing mastectomy and reconstruction in 924 breasts over 11 years.| | PubMed PubMed
- Making better doctors: a survey of premedical interns working as health coaches.| | PubMed PubMed
- Characteristics of individuals with breast cancer rearrangements in BRCA1 and BRCA2.| | PubMed PubMed
- Aggregate cost of mammography screening in the United States: comparison of current practice and advocated guidelines.| | PubMed PubMed
- Real-Time Measurement of Functional Tumor Volume by MRI to Assess Treatment Response in Breast Cancer Neoadjuvant Clinical Trials: Validation of the Aegis SER Software Platform.| | PubMed PubMed
- Mammographic screening detects low-risk tumor biology breast cancers.| | PubMed PubMed
- Development of a personalized decision aid for breast cancer risk reduction and management.| | PubMed PubMed
- Changing the terminology of cancer--reply.| | PubMed PubMed
- Optimized breast MRI functional tumor volume as a biomarker of recurrence-free survival following neoadjuvant chemotherapy.| | PubMed PubMed
- Evolving paradigm for imaging, diagnosis, and management of DCIS.| | PubMed PubMed
- Patient preferences regarding intraoperative versus external beam radiotherapy following breast-conserving surgery.| | PubMed PubMed
- Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial.| | PubMed PubMed
- Screening: biology dictates the fate of young women with breast cancer.| | PubMed PubMed
- The prognostic implications of macrophages expressing proliferating cell nuclear antigen in breast cancer depend on immune context.| | PubMed PubMed
- Impact of ductal carcinoma in situ terminology on patient treatment preferences.| | PubMed PubMed
- Overdiagnosis and overtreatment in cancer: an opportunity for improvement.| | PubMed PubMed
- Total skin-sparing mastectomy in BRCA mutation carriers.| | PubMed PubMed
- The Athena Breast Health Network: developing a rapid learning system in breast cancer prevention, screening, treatment, and care.| | PubMed PubMed
- Cost-effectiveness analysis of intraoperative radiation therapy for early-stage breast cancer.| | PubMed PubMed
- Clinically meaningful tumor reduction rates vary by prechemotherapy MRI phenotype and tumor subtype in the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).| | PubMed PubMed
- Feasibility of Performing Total Skin-Sparing Mastectomy in Patients With Prior Circumareolar Mastopexy or Reduction Mammoplasty Incisions.| | PubMed PubMed
- Reducing false-positive biopsies: a pilot study to reduce benign biopsy rates for BI-RADS 4A/B assessments through testing risk stratification and new thresholds for intervention.| | PubMed PubMed
- Recognising the benefits and harms of breast cancer screening: an opportunity to target improvement.| | PubMed PubMed
- Total skin-sparing mastectomy: a systematic review of oncologic outcomes and postoperative complications.| | PubMed PubMed
- Developing safety criteria for introducing new agents into neoadjuvant trials.| | PubMed PubMed
- Reply: The effects of acellular dermal matrix in expander-implant breast reconstruction after total skin-sparing mastectomy.| | PubMed PubMed
- An optimized five-gene multi-platform predictor of hormone receptor negative and triple negative breast cancer metastatic risk.| | PubMed PubMed
- Physician behaviors surrounding the implementation of decision and communication AIDS in a breast cancer clinic: a qualitative analysis of staff intern perceptions.| | PubMed PubMed
- Will early detection for breast cancer ever work?| | PubMed PubMed
- Adaptive trials in the neoadjuvant setting: a model to safely tailor care while accelerating drug development.| | PubMed PubMed
- Breast cancer follow-up and management after primary treatment: American Society of Clinical Oncology clinical practice guideline update.| | PubMed PubMed
- Molecular analysis of HER2 signaling in human breast cancer by functional protein pathway activation mapping.| | PubMed PubMed
- Lobular histology and response to neoadjuvant chemotherapy in invasive breast cancer.| | PubMed PubMed
- Xenografts faithfully recapitulate breast cancer-specific gene expression patterns of parent primary breast tumors.| | PubMed PubMed
- Increasing the time to expander-implant exchange after postmastectomy radiation therapy reduces expander-implant failure.| | PubMed PubMed
- Breast cancer screening: the questions answered.| | PubMed PubMed
- The impact of an electronic health questionnaire on symptom management and behavior reporting for breast cancer survivors.| | PubMed PubMed
- Adoption, acceptability, and accuracy of an online clinical trial matching website for breast cancer.| | PubMed PubMed
- Biology of breast cancer in Nigerian women: a pilot study.| | PubMed PubMed
- Whole-genome analysis informs breast cancer response to aromatase inhibition.| | PubMed PubMed
- A common language in neoadjuvant breast cancer clinical trials: proposals for standard definitions and endpoints.| | PubMed PubMed
- Evaluating the feasibility of extended partial mastectomy and immediate reduction mammoplasty reconstruction as an alternative to mastectomy.| | PubMed PubMed
- Locally advanced breast cancer: MR imaging for prediction of response to neoadjuvant chemotherapy--results from ACRIN 6657/I-SPY TRIAL.| | PubMed PubMed
- The effects of acellular dermal matrix in expander-implant breast reconstruction after total skin-sparing mastectomy: results of a prospective practice improvement study.| | PubMed PubMed
- Pathologic complete response predicts recurrence-free survival more effectively by cancer subset: results from the I-SPY 1 TRIAL--CALGB 150007/150012, ACRIN 6657.| | PubMed PubMed
- Elevated levels of proliferating and recently migrated tumor-associated macrophages confer increased aggressiveness and worse outcomes in breast cancer.| | PubMed PubMed
- Breast cancer recurrence is dictated by high-risk biology, not choice of surgery.| | PubMed PubMed
- Outcomes after total skin-sparing mastectomy and immediate reconstruction in 657 breasts.| | PubMed PubMed
- MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition.| | PubMed PubMed
- Overdiagnosis and overtreatment of breast cancer.| | PubMed PubMed
- Targeting Molecular Aberrations in Breast Cancer: Is It about Time?| | PubMed PubMed
- Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).| | PubMed PubMed
- Accelerating identification and regulatory approval of investigational cancer drugs.| | PubMed PubMed
- Proposals for uniform collection of biospecimens from neoadjuvant breast cancer clinical trials: timing and specimen types.| | PubMed PubMed
- Impact of mammographic screening on the detection of good and poor prognosis breast cancers.| | PubMed PubMed
- Outcome of long term active surveillance for estrogen receptor-positive ductal carcinoma in situ.| | PubMed PubMed
- Leukocyte composition of human breast cancer.| | PubMed PubMed
- Locally advanced breast cancers are more likely to present as Interval Cancers: results from the I-SPY 1 TRIAL (CALGB 150007/150012, ACRIN 6657, InterSPORE Trial).| | PubMed PubMed
- Elevated PCNA+ tumor-associated macrophages in breast cancer are associated with early recurrence and non-Caucasian ethnicity.| | PubMed PubMed
- Biologic markers determine both the risk and the timing of recurrence in breast cancer.| | PubMed PubMed
- A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer.| | PubMed PubMed
- Randomized phase II neoadjuvant comparison between letrozole, anastrozole, and exemestane for postmenopausal women with estrogen receptor-rich stage 2 to 3 breast cancer: clinical and biomarker outcomes and predictive value of the baseline PAM50-based int| | PubMed PubMed
- Characterizing the impact of 25 years of DCIS treatment.| | PubMed PubMed
- The impact of preoperative magnetic resonance imaging on surgical treatment and outcomes for ductal carcinoma in situ.| | PubMed PubMed
- Tumor-associated macrophages in breast cancer as potential biomarkers for new treatments and diagnostics.| | PubMed PubMed
- A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer.| | PubMed PubMed
- The Communication and Care Plan: a novel approach to patient-centered clinical information systems.| | PubMed PubMed
- Long-term prognostic role of functional limitations among women with breast cancer.| | PubMed PubMed
- Proliferating macrophages associated with high grade, hormone receptor negative breast cancer and poor clinical outcome.| | PubMed PubMed
- Intraoperative frozen section analysis of sentinel lymph nodes in breast cancer patients: a meta-analysis and single-institution experience.| | PubMed PubMed
- Impact of chemotherapy on postoperative complications after mastectomy and immediate breast reconstruction.| | PubMed PubMed
- Lessons learned from genetic testing.| | PubMed PubMed
- Expanding the reach of decision and communication aids in a breast care center: a quality improvement study.| | PubMed PubMed
- Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial.| | PubMed PubMed
- Is radiation indicated in patients with ductal carcinoma in situ and close or positive mastectomy margins?| | PubMed PubMed
- Solving the overdiagnosis dilemma.| | PubMed PubMed
- Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer.| | PubMed PubMed
- Application of screening principles to the reconstructed breast.| | PubMed PubMed
- Rethinking screening for breast cancer and prostate cancer.| | PubMed PubMed
- Bacteriologic features of surgical site infections following breast surgery.| | PubMed PubMed
- Pathologic and biologic response to preoperative endocrine therapy in patients with ER-positive ductal carcinoma in situ.| | PubMed PubMed
- A comparison of RNA amplification techniques at sub-nanogram input concentration.| | PubMed PubMed
- I-SPY 2: an adaptive breast cancer trial design in the setting of neoadjuvant chemotherapy.| | PubMed PubMed
- Improved surgical outcomes for breast cancer patients receiving neoadjuvant aromatase inhibitor therapy: results from a multicenter phase II trial.| | PubMed PubMed
- Prognostic implications of positive nonsentinel lymph nodes removed during selective sentinel lymphadenectomy for breast cancer.| | PubMed PubMed
- Oncologist use of the Adjuvant! model for risk communication: a pilot study examining patient knowledge of 10-year prognosis.| | PubMed PubMed
- The UCSC Cancer Genomics Browser.| | PubMed PubMed
- Hypertension is an independent predictor of survival disparity between African-American and white breast cancer patients.| | PubMed PubMed
- Total skin-sparing mastectomy: complications and local recurrence rates in 2 cohorts of patients.| | PubMed PubMed
- When informed, all women do not prefer breast conservation.| | PubMed PubMed
- Sensitivity to input variability of the Adjuvant! Online breast cancer prognostic model.| | PubMed PubMed
- Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature.| | PubMed PubMed
- Converting evidence to practice: a guide for the clinical application of MRI for the screening and management of breast cancer.| | PubMed PubMed
- Is it necessary to harvest additional lymph nodes after resection of the most radioactive sentinel lymph node in breast cancer?| | PubMed PubMed
- Monitoring the implementation of Consultation Planning, Recording, and Summarizing in a breast care center.| | PubMed PubMed
- Invasive breast cancer: predicting disease recurrence by using high-spatial-resolution signal enhancement ratio imaging.| | PubMed PubMed
- Risk communication with patients with breast cancer: cautionary notes about printing Adjuvant! estimates.| | PubMed PubMed
- Estrogen receptor-negative breast cancer is less likely to arise among lipophilic statin users.| | PubMed PubMed
- Statement of the science concerning locoregional treatments after preoperative chemotherapy for breast cancer: a National Cancer Institute conference.| | PubMed PubMed
- Multiplexed cell signaling analysis of human breast cancer applications for personalized therapy.| | PubMed PubMed
- Training community resource center and clinic personnel to prompt patients in listing questions for doctors: follow-up interviews about barriers and facilitators to the implementation of consultation planning.| | PubMed PubMed
- Optimizing the total skin-sparing mastectomy.| | PubMed PubMed
- A role for biomarkers in the screening and diagnosis of breast cancer in younger women.| | PubMed PubMed
- Treatment with autologous antigen-presenting cells activated with the HER-2 based antigen Lapuleucel-T: results of a phase I study in immunologic and clinical activity in HER-2 overexpressing breast cancer.| | PubMed PubMed
- Fluorescence in situ hybridization of ductal lavage samples identifies malignant phenotypes from cytologically normal cells in women with breast cancer.| | PubMed PubMed
- Pilot trial of a computerized decision aid for breast cancer prevention.| | PubMed PubMed
- Ductal carcinoma in situ in BRCA mutation carriers.| | PubMed PubMed
- Analysis of molecular inversion probe performance for allele copy number determination.| | PubMed PubMed
- Genomic and transcriptional aberrations linked to breast cancer pathophysiologies.| | PubMed PubMed
- Type and duration of exogenous hormone use affects breast cancer histology.| | PubMed PubMed
- Biologic significance of false-positive magnetic resonance imaging enhancement in the setting of ductal carcinoma in situ.| | PubMed PubMed
- Magnetic resonance imaging captures the biology of ductal carcinoma in situ.| | PubMed PubMed
- Breast cancer growth prevention by statins.| | PubMed PubMed
- Evaluation of a visit preparation intervention implemented in two rural, underserved counties of Northern California.| | PubMed PubMed
- Challenge with mammary tumor cells expressing MHC class II and CD80 prevents the development of spontaneously arising tumors in MMTV-neu transgenic mice.| | PubMed PubMed
- Clinical trials are required to prove the chemopreventive worth of statins.| | PubMed PubMed
- A call for clinical trials: lipophilic statins may prove effective in treatment and prevention of particular breast cancer subtypes.| | PubMed PubMed
- Mammographic, sonographic, and pathologic characteristics of Burkitt's lymphoma in a patient referred for diagnostic mammography.| | PubMed PubMed
- Breast cancer risk assessment and prevention: a framework for shared decision-making consultations.| | PubMed PubMed
- Genetic/familial high-risk assessment: breast and ovarian.| | PubMed PubMed
- Statins: health-promoting agents show promise for breast cancer prevention.| | PubMed PubMed
- Tamoxifen may prevent both ER+ and ER- breast cancers and select for ER- carcinogenesis: an alternative hypothesis.| | PubMed PubMed
- Genetic testing in an ethnically diverse cohort of high-risk women: a comparative analysis of BRCA1 and BRCA2 mutations in American families of European and African ancestry.| | PubMed PubMed
- Primary tumor characteristics predict sentinel lymph node macrometastasis in breast cancer.| | PubMed PubMed
- The effect of sentinel node tumor burden on non-sentinel node status and recurrence rates in breast cancer.| | PubMed PubMed
- Ratio of positive to total number of sentinel nodes predicts nonsentinel node status in breast cancer patients.| | PubMed PubMed
- MRI measurements of breast tumor volume predict response to neoadjuvant chemotherapy and recurrence-free survival.| | PubMed PubMed
- Mapping molecular networks using proteomics: a vision for patient-tailored combination therapy.| | PubMed PubMed
- Immune dysfunction and micrometastases in women with breast cancer.| | PubMed PubMed
- Integration of imaging in the management of breast cancer.| | PubMed PubMed
- Development of a novel method for measuring in vivo breast epithelial cell proliferation in humans.| | PubMed PubMed
- Safety of immediate transverse rectus abdominis myocutaneous breast reconstruction for patients with locally advanced disease.| | PubMed PubMed
- Internal mammary sentinel lymph node mapping for invasive breast cancer: implications for staging and treatment.| | PubMed PubMed
- Recruitment, genetic counseling, and BRCA testing for underserved women at a public hospital.| | PubMed PubMed
- Accuracy of selective sentinel lymphadenectomy after neoadjuvant chemotherapy: effect of clinical node status at presentation.| | PubMed PubMed
- Evaluation of breast cancer risk assessment techniques: a cost-effectiveness analysis.| | PubMed PubMed
- Clonality of lobular carcinoma in situ and synchronous invasive lobular carcinoma.| | PubMed PubMed
- Applying the neoadjuvant paradigm to ductal carcinoma in situ.| | PubMed PubMed
- Neoadjuvant chemotherapy for primary breast cancer: lessons learned and opportunities to optimize therapy.| | PubMed PubMed
- Neoadjuvant hormonal therapy for ductal carcinoma in situ: trial design and preliminary results.| | PubMed PubMed
- An XML message broker framework for exchange and integration of microarray data.| | PubMed PubMed
- Racial differences in mammographic breast density.| | PubMed PubMed
- Cyclooxygenase-2 expression is related to nuclear grade in ductal carcinoma in situ and is increased in its normal adjacent epithelium.| | PubMed PubMed
- Magnetic resonance imaging in patients diagnosed with ductal carcinoma-in-situ: value in the diagnosis of residual disease, occult invasion, and multicentricity.| | PubMed PubMed
- MHC class II enhanceosome: how is the class II transactivator recruited to DNA-bound activators?| | PubMed PubMed
- Failure to harvest sentinel lymph nodes identified by preoperative lymphoscintigraphy in breast cancer patients.| | PubMed PubMed
- Efficacy of computerized infrared imaging analysis to evaluate mammographically suspicious lesions.| | PubMed PubMed
- Improving the quality of decision making in breast cancer: consultation planning template and consultation recording template.| | PubMed PubMed
- Accuracy of MR imaging for revealing residual breast cancer in patients who have undergone neoadjuvant chemotherapy.| | PubMed PubMed
- Axillary metastasis from a malignant mullerian mixed tumor.| | PubMed PubMed
- Major histocompatibility complex class II transcriptional platform: assembly of nuclear factor Y and regulatory factor X (RFX) on DNA requires RFX5 dimers.| | PubMed PubMed
- Pretest prediction of BRCA1 or BRCA2 mutation by risk counselors and the computer model BRCAPRO.| | PubMed PubMed
- Consultation planning to help breast cancer patients prepare for medical consultations: effect on communication and satisfaction for patients and physicians.| | PubMed PubMed
- Epithelial and fibroblast cell lines derived from a spontaneous mammary carcinoma in a MMTV/neu transgenic mouse.| | PubMed PubMed
- Magnetic resonance imaging for primary breast cancer management: current role and new applications.| | PubMed PubMed
- Skin-sparing mastectomy and immediate breast reconstruction: a prospective cohort study for the treatment of advanced stages of breast carcinoma.| | PubMed PubMed
- New approaches to the imaging, diagnosis, and biopsy of breast lesions.| | PubMed PubMed
- Improving the accuracy of mammography: volume and outcome relationships.| | PubMed PubMed
- Ductal lavage for detection of cellular atypia in women at high risk for breast cancer.| | PubMed PubMed
- Does timely assessment affect the anxiety associated with an abnormal mammogram result?| | PubMed PubMed
- MRI phenotype is associated with response to doxorubicin and cyclophosphamide neoadjuvant chemotherapy in stage III breast cancer.| | PubMed PubMed
- The impact of alternative practices on the cost and quality of mammographic screening in the United States.| | PubMed PubMed
- Ductal growth is impeded in mammary glands of C-neu transgenic mice.| | PubMed PubMed
- MR imaging of the breast in patients with positive margins after lumpectomy: influence of the time interval between lumpectomy and MR imaging.| | PubMed PubMed
- Integration of breast imaging into cancer management.| | PubMed PubMed
- Dynamic high-spatial-resolution MR imaging of suspicious breast lesions: diagnostic criteria and interobserver variability.| | PubMed PubMed
- Current national health insurance coverage policies for breast and ovarian cancer prophylactic surgery.| | PubMed PubMed
- Building bridges between physicians and patients: results of a pilot study examining new tools for collaborative decision making in breast cancer.| | PubMed PubMed
- Management of ductal carcinoma in situ.| | PubMed PubMed
- Biological therapies for breast carcinoma: concepts for improvement in survival.| | PubMed PubMed
- Prophylactic mastectomy in women with a high risk of breast cancer.| | PubMed PubMed
- Vaccination with the extracellular domain of p185neu prevents mammary tumor development in neu transgenic mice.| | PubMed PubMed
- Contrast-Enhanced Magnetic Resonance Imaging to Assess Tumor Histopathology and Angiogenesis in Breast Carcinoma.| | PubMed PubMed
- Utility of magnetic resonance imaging in the management of breast cancer: evidence for improved preoperative staging.| | PubMed PubMed
- A multicenter randomized trial of DIAC for cyclical mastopathy.| | PubMed PubMed
- Is routine frozen section assessment feasible in the practice environment of the 1990s?| | PubMed PubMed
- Hormone replacement therapy and breast cancer risk.| | PubMed PubMed
- Ultrasound tissue characterization of breast biopsy specimens: expanded study.| | PubMed PubMed
- Barriers to care and treatment: the challenge of daily radiation therapy.| | PubMed PubMed
- Should we recommend screening mammography for women aged 40 to 49?| | PubMed PubMed
- Breast.| | PubMed PubMed
- Trade-offs between survival and breast preservation for three initial treatments of ductal carcinoma-in-situ of the breast.| | PubMed PubMed
- Potentially ineffective care. A new outcome to assess the limits of critical care.| | PubMed PubMed
- Cost per anomaly: what does a diaphragmatic hernia cost?| | PubMed PubMed
- An epitope on the transferrin receptor preferentially exposed during tumor progression in human lymphoma is close to the ligand binding site.| | PubMed PubMed
- Follicular lymphoma: a model of lymphoid tumor progression in man.| | PubMed PubMed
- Idiotype vaccination against murine B cell lymphoma. Humoral and cellular requirements for the full expression of antitumor immunity.| | PubMed PubMed
- Development of a new therapeutic approach to B cell malignancy. The induction of immunity by the host against cell surface receptor on the tumor.| | PubMed PubMed
- Immunotherapy of established murine B cell lymphoma. Combination of idiotype immunization and cyclophosphamide.| | PubMed PubMed
- Myocardial performance and extracellular ionized calcium in a severely failing human heart.| | PubMed PubMed
- A novel method for emergency immobilization of the wrist during cross-country skiing.| | PubMed PubMed
 
    